SpecTruth DAO

SpecTruth DAO

Mental Health

Spectruth DAO is revolutionizing mental health by uniting science, AI, and community to predict and prevent PTSD. Our mission: early detection and personalized care through epigenetic testing, wearables, and open collaboration—empowering healing for all. Join us!

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Market Hypothesis

Over 300 million

Patient Population Size worldwide

$232 billion annually

PTSD costs the global economy

$10 billion by 2030

Market Opportunity for Precision Diagnostics projected

Spectruth is pioneering precision mental health—using saliva-based epigenetic tests, AI, and wearables to predict, prevent, and personalize PTSD care worldwide.


Additional documentation

📄 Download litepaper

Post-Traumatic Stress Disorder (PTSD) remains a massive, costly, and often invisible crisis, impacting over 300 million people and costing the global economy more than $232 billion annually. Traditional approaches are reactive and generic, failing to...

Research Focus Areas
Epigenetic Biomarker

Epigenetic Biomarker

Identifying and validating DNA methylation markers in saliva that predict PTSD risk, onset, and treatment response, especially in high-risk groups like military personnel and veterans to enable early, preemptive detection and personalized care, moving beyond symptom-based diagnosis.


Wearable and Digital Health

Wearable and Digital Health

Utilizing wearable devices (for vitals) and EEG technology to continuously monitor physiological and neurological signals associated with stress and trauma to collect real-time, multi-modal data to enhance predictive models and support dynamic, personalized interventions.


AI-Driven Personalization and Data Analytics

AI-Driven Personalization and Data Analytics

Applying advanced machine learning and agentic AI to analyze large, multi-modal datasets (epigenetics, EEG, wearables, clinical outcomes) to develop algorithms and integration platforms that match individuals to optimal treatments and refine intervention protocols based on real-world data.


Team & Community
James Holz

James Holz

JD

Founder of Spectruth DAO, pioneering precision mental health through AI, blockchain, and epigenetics. Inspired by his veteran father’s...

Usmon Yuldashev

Usmon Yuldashev

MD

Dr Usman's career reflects a steadfast dedication to improving patient outcomes through expertise, compassion, and continuous learning. I...

Iryna Bezborodko-Holz

Iryna Bezborodko-Holz

Project Management of Various Complexities: Cryptocurrency Wallets, Online Casinos, Creation and Launch of Marketing Strategies in Projects.

Alexander Orlov

Alexander Orlov

OD

Dr. Alexander Orlov, DO, is a board-certified physician with over 30 years of experience in family and regenerative...

@SpectruthAI on 𝕏

Discord community

Telegram community

Project Roadmap
Q3 2025
Initiate Ibogaine and PTSD Research
Q4 2025
Integrate all data collection onto Hippo Protocol Mainnet, Begin ML training, Launch targeted marketing campaign
Q1 2026
Publish data, Begin ML analysis of data, Expand clinical trials, Open Holz Clinic, Secure partnerships with insurance providers
Q2 2026
Launch limited rollout of personalized therapy, Partner with clinics to expand reach
Q3 2026
Develop saliva based PTSD testing, Manufacture synthetic Ibogaine
2026 and ahead
Reward DAO holders with the profits generated using its IP, Expand biomarker research for additional mental health disorders
Recommended Reads
Epigenetic Alterations in Post-Traumatic Stress Disorder

Complex Psychiatry

Epigenetic Alterations in Post-Traumatic Stress Disorder


A review of epigenetic contributions 
to post-traumatic stress disorder

Dialogues in Clinical Neuroscience

A review of epigenetic contributions 
to post-traumatic stress disorder


Epigenetic signatures of intergenerational exposure to violence in three generations of Syrian refugees

Scientific Reports

Epigenetic signatures of intergenerational exposure to violence in three generations of Syrian refugees